Pandemic versus Epidemic Influenza Mortality: A Pattern of Changing Age Distribution
نویسندگان
چکیده
منابع مشابه
Pandemic versus epidemic influenza mortality: a pattern of changing age distribution.
Almost all deaths related to current influenza epidemics occur among the elderly. However, mortality was greatest among the young during the 1918-1919 pandemic. This study compared the age distribution of influenza-related deaths in the United States during this century's three influenza A pandemics with that of the following epidemics. Half of influenza-related deaths during the 1968-1969 infl...
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Experimental and epidemiologic evidence indicates that variations of absolute humidity account for the onset and seasonal cycle of epidemic influenza in temperate regions. A role for absolute humidity in the transmission of pandemic influenza, such as 2009 A/H1N1, has yet to be demonstrated and, indeed, outbreaks of pandemic influenza during more humid spring, summer, and autumn months might ap...
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BACKGROUND Pandemic influenza is said to 'shift mortality' to younger age groups; but also to spare a subpopulation of the elderly population. Does one of these effects dominate? Might this have important ramifications? METHODS We estimated age-specific excess mortality rates for all-years for which data were available in the 20th century for Australia, Canada, France, Japan, the UK, and the ...
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Younger age groups account for proportionally more mortality in influenza pandemics than in seasonal influenza epidemics. Mechanisms that might explain this include young people suffering from an over-reactive immune system ("cytokine storm"), older people benefiting from cross-immunity from a wider variety of previous influenza infections ("antigenic history"), and lifetime immune responses in...
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Influenza viruses, which are responsible for annual outbreaks, can exist in any of 198 possible influenza subtypes resulting from the combinations of 18 hemagglutinin and 11 neuraminidase types. However, the number of subtypes capable of infecting humans has never been predicted or investigated. Influenza virus outbreaks that occur every year can be categorized as follows: a pandemic with high ...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 1998
ISSN: 0022-1899,1537-6613
DOI: 10.1086/515616